Recently I gave a talk about 'Closing The Loop', which fairly well describes both my long and short term goals. The intersection of our biology with technology is where humans have the greatest potential to accelerate our understanding of the universe.
Examples of this start at having greater transparency into others heart beats to more intelligently interact. Beyond that we could have more complete transparency into how our bodies work, so we can aggregate data to improve health and overcome our physical limitations. Beyond that, is a higher bandwidth means of communicating with each other and machines.